Phenolyzer stands for Phenotype Based Gene Analyzer, a tool focusing on discovering genes based on user-specific disease/phenotype terms.

Get Started Post result

Please use semicolon or enter as separators. Like "alzheimer;brain".
Try to use multiple terms instead of a super long term
OMIM IDs are also accepted, like 114480 for 'Breast cancer'
Please enter 'HP:0002459;HP:0010522;HP:0001662' as HPO IDs.
Please separate genes by semicolon or enter. Entrez IDs are also accepted here.
Bed File


OMIM, HPO, HumanDO, GWAS_Catalog and ClinVar databases are updated


OMIM database is updated


Phenolyzer webserver is being migrated! You may experience page loading problems and other issues.


OMIM database is now updated to 2016-08-04 version!


OMIM database is now updated to 2016-01-24 version!


Due to copyright issues, GeneCards database is no longer provided in Phenolyzer.


Dear all, you might have experienced some changes in your result. Don't panic! There's been several big updates in NCBI's Biosystem database. We recently noticed it and updated the database in Phenolyzer! Toast!


1) OMIM database was updated to 2015-11-19

2) We added a functionality specifically for Chinese, now you can entern chinese and click 'Translate' to translate your disease into English!


OMIM database was updated again.


Now the HPO Identifiers are supported. For example, please enter 'HP:0002459; HP:0010522; HP:0001662'.


The HPO ontology and anotation, DO ontology, and OMIM disease synonyms are updated to the newest version!


The OMIM,GWAS Catalog, ClinVar databases are updated to the newest version!


Two additional gene scores were added into Phenolyzer as annotations: Gene Haploinsufficiency Score for dominant disease genes, and Gene Intolerance Score for severe disease genes


Several important databases are integrated as the form of plugins: Mentha protein-protein interaction database for gene-gene mapping, , DisGenet gene-disease database, Genetic Association Database, GeneCards for disease-gene mapping!