Phenolyzer

Phenolyzer stands for Phenotype Based Gene Analyzer, a tool focusing on discovering genes based on user-specific disease/phenotype terms.

Get Started Post result

Phenolyzer server is updated on 12/3/2018. When you input a disease name (such as "Alzheimer's disease"), make sure to select "Phenotype Interpret" to "Disease Only" mode.

Please use semicolon or enter as separators. Like "alzheimer;brain".
Try to use multiple terms instead of a super long term
OMIM IDs are also accepted, like 114480 for 'Breast cancer'
Please enter 'HP:0002459;HP:0010522;HP:0001662' as HPO IDs.
Please separate genes by semicolon or enter. Entrez IDs are also accepted here.
Bed File


Hui Yang, Peter N. Robinson, Kai Wang. Phenolyzer: phenotype-based prioritization of candidate genes for human diseases. Nature Methods, 12:841-843 (2015).

[12/03/2018]

Phenolyzer server is updated to match Phenolyzer new version, with improved handling of HPO terms and more extensive phenotype expansion on input terms.

[03/30/2017]

OMIM database is updated

[02/07/2017]

Phenolyzer webserver is being migrated! You may experience page loading problems and other issues.

[08/04/2016]

OMIM database is now updated to 2016-08-04 version!

[01/24/2016]

OMIM database is now updated to 2016-01-24 version!

[01/05/2016]

Due to copyright issues, GeneCards database is no longer provided in Phenolyzer.

[12/02/2015]

Dear all, you might have experienced some changes in your result. Don't panic! There's been several big updates in NCBI's Biosystem database. We recently noticed it and updated the database in Phenolyzer! Toast!